Hereditary cancer accounts for nearly 5-10% of all cancers. With early detection through appropriate screening methods and prophylactic measures, the chances of prevention and successful treatment are higher.

The integration of cancer genetics in clinical practice enables physicians to distinguish a proportion of patients that have inherited mutations with increased risk susceptibility to certain cancers. The identification of such germline mutations allows for targeted cancer surveillance and prevention.

PreSENTIA, with an extensive portfolio of 19 hereditary cancer panels, tests for numerous inherited genetic mutations that could cause cancer in the future.

WHAT IS PreSENTIA?

PreSENTIA consists of an extensive portfolio of 19 hereditary cancer panels. The genes selected have been shown to predispose to certain hereditary cancer syndromes (cancer predisposition syndromes), and hereditary cancers.

The patients’ medical family history, their ethnicity, and any physical findings present linked to cancer should always be taken into consideration.

PreSENTIA offers 18 cancer-specific gene panels, and 1 hereditary pan- cancer panel that covers 62 genes and 24 predisposing cancer syndromes associated with hereditary cancer.

PreSENTIA is a new generation test for identifying genetic mutations with cancer susceptibility. It has an extensive portfolio of 19 hereditary cancer panels. Each panel focuses on a specific set of genes that have high susceptibility to cancer predisposing syndromes, that in turn have increased risk of causing cancer.

BENEFITS OF PreSENTIA INCLUDE:

  • Clinically actionable mutations
  • Proven technology
  • Easy-to-interpret results
  • Short turn-around time

The same mutation can cause cancer earlier in some family members than others, or not develop into cancer at all.

WHO IS THIS TEST FOR?

According to genetic testing guidelines* for cancer, people who might benefit from genetic testing are those that have:

  • Family members with cancer in the same side of the family
  • Multiple cancers in the same family member
  • Family members with early cancer onset
  • Family members with rare cancer types
  • A family member that has been diagnosed with a genetic mutation that has cancer susceptibility
  • Personal or family history of a hereditary cancer syndrome

The patients’ medical family history, their ethnicity, and any physical findings present linked to cancer should always be taken into consideration.

Additionally, patients already diagnosed with cancer can take PreSENTIA if their family history is suggestive of an inherited genetic change running in their family. PreSENTIA can let them know if their cancer is hereditary, which will help to:

  • Improve disease classification
  • Inform other family members of their risk
  • Enhance clinical management

* Data adapted from: American Cancer Society, National Cancer Institute, American Society of Clinical Oncology and American College of Obstetricians and Gynecologists.

UNIQUE FEATURES

TARGETED TECHNOLOGY

PreSENTIA is based on a novel, target capture enrichment technology that has been validated for its accuracy and precision.

HIGH READ DEPTH

Specifically-designed genetic and bioinformatics methods have been incorporated to ensure high read-depths, raising the sensitivity and specificity of the test.

MULTI-ENGINE ANALYSIS

Proprietary bioinformatics pipelines analyze the sequencing data produced from each sample, increasing the sensitivity and specificity of PreSENTIA

WHY RECOMMEND PreSENTIA TO MY PATIENTS?

Identifying the genetic mutations that could cause cancer in the future is useful for people with cancer in their family history, and for people suspected of having a hereditary form of cancer. This knowledge can help with better medical planning and avoiding risk factors.

WHAT ARE THE BENEFITS FOR MY PATIENTS?

  • Ability to select a panel that is most suited to them
  • Targeted cancer monitoring to detect cancer early, when treatment is more beneficial
  • Prevention of cancer by prophylactic measures
  • Invaluable information for family members that might carry the same mutation
  • Improved clinical care

HOW DOES PreSENTIA HELP ME?

PreSENTIA gives you helpful insight into the genetic makeup of your patient in an efficient, rapid and comprehensive way.

Receiving information about your patient's risk of developing cancer early allows you to look into the most appropriate prophylactic measures and therapy options.

You can develop a better clinical management plan for your patient and any of their family members who might also be affected.

WHAT CAN I DO TO HELP MY PATIENTS AFTER TAKING PreSENTIA?

  • Recommend screening tests at key interval timepoints for early cancer detection
  • Recommend prophylactic measures
  • Recommend testing for immediate family members who might be at risk

WHAT DOES IT TEST FOR?

HEREDITARY CANCER PANELS

  • BREAST & GYNAECOLO­GICAL

    26

    BREAST/GYNAECOLOGICAL HEREDITARY GENE PANEL

    Description

    The PreSentia hereditary breast/gynaecological cancer panel tests for numerous inherited genetic alterations that could cause Breast, Ovarian or Endometrial cancers in the future. Identifying these mutations is empowering for healthcare providers and for patients, as it allows them to take better and more informed decisions.

    Who is this test for?

    According to genetic testing guidelines, people who might benefit from genetic testing for breast/gynaecological cancers are those that have:

    • More than 2 family members with cancer in the same side of the family
    • Multiple cancers in the same family member
    • Family members with early cancer onset
    • Family members with rare cancer types
    • A family member with multiple cancers
    • A family member that has been diagnosed with a genetic mutation that has cancer susceptibility
    • History of previous malignancies

    TAT:
    14 days
    Sample:
    Buccal Swab
    No of Genes Tested:
    26
    No of related hereditary cancer syndromes:
    10

    Genes Tested

    ATM, BARD1, BRCA1, BRCA2, BRIP1, CDH1, CHEK2, DICER1, EPCAM, MLH1, MRE11A, MSH2, MSH6, MUTYH, NBN, PALB2, PMS2, POLD1, POLE, PTEN, RAD50, RAD51C, RAD51D, SMARCA4, STK11, TP53

    Hereditary Cancer Syndromes associated with this panel:

    • Hereditary Breast & Ovarian cancer syndrome (BRCA1, BRCA2) (Associated cancers: Breast, Ovarian, Prostate, Pancreatic, Melanoma, Stomach, Esophagus)
    • Li-Fraumeni syndrome (TP53) (Associated cancers: Breast, Ovarian, Prostate, Pancreatic, Colorectal, Gastric, Renal, Sarcomas, Brain tumors, Lung, Leukemia)
    • Li-Fraumeni syndrome 2 (CHEK2) (Associated cancers: Breast, Sarcomas, Brain tumors)
    • PTEN Hamartoma syndrome (PTEN) (Associated cancers: Breast, Endometrial, Colorectal, Melanoma, Renal)
    • Peutz-Jeghers syndrome (STK11) (Associated cancers: Breast, Ovarian, Endometrial, Colorectal, Gastric, Pancreatic)
    • Hereditary diffuse gastric syndrome (CDH1) (Associated cancers: Stomach, Breast)
    • MUTYH-associated polyposis syndrome (MUTYH) (Associated cancers: Colorectal)
    • Lynch syndrome (MLH1, MSH2, MSH6, PMS2, EPCAM) (Associated cancers: Colorectal, Endometrial, Stomach, Ovarian, Prostate, Pancreatic, Renal)
    • Ataxia-telangiectasia syndrome (ATM) (Associated cancers: Leukemia, Lymphoma)
    • DICER 1 syndrome (DICER1) (Associated cancers: Lung, Renal, Ovarian, Thyroid cancer)
    • Polymerase Proofreading Associated syndrome (POLD1, POLE) (Associated cancers: Colorectal, Endometrial)
    • Constitutional mismatch repair syndrome (MSH2, MSH6, MLH1, PMS2) (Associated cancers: Hematologic malignancies, Brain tumors, Gastrointestinal cancers, Colorectal tumors)

  • BREAST CANCER GUIDELINES - BASED

    19

    HEREDITARY BREAST/GYNECOLOGICAL CANCER GUIDELINES-BASED PANEL

    Description

    The PreSENTIA hereditary breast cancer guidelines-based panel tests for numerous inherited genetic mutations that could cause Breast, Ovarian, Endometrial or associated cancers in the future. Identifying mutations in these genes empowers healthcare providers and patients, as it allows them to take better and more informed decisions.

    Who is this test for?

    According to genetic testing guidelines, people who might benefit from genetic testing for hereditary cancers are those that have:

    • Several family members in the same side of the family with cancer
    • Multiple cancers in the same family member
    • Family members with early cancer onset
    • Family members with rare cancer types
    • A family member that has been diagnosed with a genetic mutation that has cancer susceptibility
    • History of previous malignancies

    TAT:
    2-3 weeks
    Sample:
    Buccal Swab
    No of Genes Tested:
    19
    No of related hereditary cancer syndromes:
    7

    Genes Tested

    ATM, CDH1, MSH6, RAD51C, BARD1, CHEK2, NBN, RAD51D, BRCA1, EPCAM, PALB2, TP53, BRCA2, MLH1, PMS2, STK11, BRIP1, MSH2, PTEN

    Hereditary Cancer Syndromes associated with this panel:

    • Hereditary Breast & Ovarian cancer syndrome (BRCA1, BRCA2) (Associated cancers: Breast, Ovarian, Prostate, Pancreatic, Melanoma, Gastric, Esophagus)
    • Li-Fraumeni syndrome (TP53) (Associated cancers: Breast, Ovarian, Prostate, Pancreatic, Colorectal, Gastric, Renal, Sarcomas, Brain tumors, Lung, Leukemia)
    • Li-Fraumeni syndrome 2 (CHEK2) (Associated cancers: Breast, Sarcomas, Brain tumors)
    • Lynch syndrome (MLH1, MSH2, MSH6, PMS2, EPCAM) (Associated cancers: Colorectal, Endometrial, Stomach, Ovarian, Prostate, Pancreatic, Renal)
    • Peutz-Jeghers syndrome (STK11) (Associated cancers: Breast, Ovarian, Endometrial, Colorectal, Gastric, Pancreatic)
    • PTEN Hamartoma syndrome (PTEN) (Associated cancers: Breast, Endometrial, Colorectal, Melanoma, Renal)
    • Hereditary diffuse gastric syndrome (CDH1) (Associated cancers: Gastric, Breast)

  • BREAST CANCER
    HIGH-RISK

    7

    HEREDITARY BREAST CANCER HIGH-RISK PANEL

    Description

    The PreSENTIA hereditary breast cancer high-risk panel tests for numerous, high-risk inherited genetic mutations that could cause Breast, Ovarian, Endometrial or associated cancers in the future. Identifying mutations in these genes empowers healthcare providers and patients, as it allows them to take better and more informed decisions.

    Who is this test for?

    According to genetic testing guidelines, people who might benefit from genetic testing for hereditary cancers are those that have:

    • Several family members in the same side of the family with cancer
    • Multiple cancers in the same family member
    • Family members with early cancer onset
    • Family members with rare cancer types
    • A family member that has been diagnosed with a genetic mutation that has cancer susceptibility
    • History of previous malignancies

    TAT:
    2-3 weeks
    Sample:
    Buccal Swab
    No of Genes Tested:
    7
    No of related hereditary cancer syndromes:
    5

    Genes Tested

    BRCA1,BRCA2,CDH1,PALB2,PTEN,TP53,STK11

    Hereditary Cancer Syndromes associated with this panel:

    • Hereditary Breast & Ovarian cancer syndrome (BRCA1, BRCA2) (Associated cancers: Breast, Ovarian, Prostate, Pancreatic, Melanoma, Gastric, Esophagus)
    • Li-Fraumeni syndrome (TP53) Associated cancers: (Breast, Ovarian, Prostate, Pancreatic, Colorectal, Gastric, Renal, Sarcomas, Brain tumors, Lung, Leukemia)
    • PTEN Hamartoma syndrome (PTEN) (Associated cancers: Breast, Endometrial, Colorectal, Melanoma, Renal)
    • Peutz-Jeghers syndrome (STK11) (Associated cancers: Breast, Ovarian, Endometrial, Colorectal, Gastric, Pancreatic)
    • Hereditary diffuse gastric syndrome (CDH1) (Associated cancers: Gastric, Breast)

  • BRCA1 / BRCA2

    2

    HEREDITARY BRCA1 / BRCA2 CANCER PANEL

    Description

    The PreSENTIA hereditary BRCA1/BRCA2 cancer panel tests for BRCA1 and BRCA2 genetic mutations that could cause specific cancers in the future. Identifying mutations in these genes empowers healthcare providers and patients, as it allows them to take better and more informed decisions.

    Who is this test for?

    According to genetic testing guidelines, people who might benefit from genetic testing for hereditary cancers caused by mutations in the BRCA1/BRCA2 genes are those that have:

    • Several family members with cancer in the same side of the family
    • Multiple cancers in the same family member
    • Family members with early cancer onset
    • Family members with rare cancer types
    • A family member that has been diagnosed with a genetic mutation that has cancer susceptibility
    • History of previous malignancies

    TAT:
    2-3 weeks
    Sample:
    Buccal Swab
    No of Genes Tested:
    2
    No of related hereditary cancer syndromes:
    1

    Genes Tested

    BRCA1 ,BRCA2

    Hereditary Cancer Syndromes associated with this panel:

    • Hereditary Breast & Ovarian cancer syndrome (BRCA1, BRCA2) (Associated Cancers: Breast, Ovarian, Prostate, Pancreatic, Melanoma, Gastric, Esophagus)

  • COLORECTAL

    17

    HEREDITARY COLORECTAL CANCER PANEL

    Description

    The PreSENTIA hereditary colorectal cancer panel tests for numerous inherited genetic mutations that could cause colorectal cancers in the future. Identifying mutations in these genes empowers healthcare providers and patients, as it allows them to take better and more informed decisions.

    Who is this test for?

    According to genetic testing guidelines, people who might benefit from genetic testing for hereditary cancers are those that have:

    • At least 1 first-degree family member with colorectal cancer
    • Personal or family history of colorectal polyps or colorectal cancer
    • Personal history of a confirmed or suspected hereditary colorectal cancer syndrome
    • Family members diagnosed with cancer at a young age
    • Family members diagnosed with rare forms of cancer
    • Multiple cancers in the same family member
    • At least one family member with genetic testing confirming genetic mutation
    • Personal history of previous malignancies

    TAT:
    2-3 weeks
    Sample:
    Buccal Swab
    No of Genes Tested:
    17
    No of related hereditary cancer syndromes:
    12

    Genes Tested

    APC, MLH1, POLE, BMPR1A, MSH2, PTEN, CDH1, MSH6, SMAD4, CHEK2, MUTYH, STK11, EPCAM, PMS2, TP53, GREM1, POLD1

    Hereditary Cancer Syndromes associated with this panel:

    • Familial Adenomatous Polyposis / Attenuated Familial Adenomatous Polyposis (APC) (Associated cancers: Gastric, Pancreatic, Colorectal, Osteomas, Small Bowel)
    • Li-Fraumeni syndrome (TP53) (Associated cancers: Breast, Ovarian, Prostate, Pancreatic, Colorectal, Gastric, Renal, Sarcomas, Brain tumors, Lung, Leukemia)
    • Li-Fraumeni syndrome 2 (CHEK2) (Associated cancers: Breast, Sarcomas, Brain tumors)
    • PTEN Hamartoma syndrome (PTEN) (Associated cancers: Breast, Endometrial, Colorectal, Melanoma, Renal)
    • Peutz-Jeghers syndrome (STK11) (Associated cancers: Breast, Ovarian, Endometrial, Colorectal, Gastric, Pancreatic)
    • Hereditary diffuse gastric syndrome (CDH1) (Associated cancers: Gastric, Breast)
    • MUTYH-associated polyposis syndrome (MUTYH) (Associated cancer: Colorectal)
    • Lynch syndrome (MLH1, MSH2, MSH6, PMS2, EPCAM) (Associated cancers: Colorectal, Endometrial, Gastric, Ovarian, Prostate, Pancreatic, Renal)
    • Polymerase Proofreading Associated syndrome (POLD1, POLE) (Associated cancers: Colorectal, Endometrial)
    • Hereditary mixed polyposis syndrome (GREM1) (Associated cancer: Colorectal)
    • Juvenile Polyposis syndrome (SMAD4, BMPR1A) (Associated cancers: Colorectal, Gastric, Pancreatic)
    • Constitutional Mismatch Repair syndrome (MSH2, MSH6, MLH1, PMS2) (Associated cancers: Hematologic malignancies, Brain tumors, Gastrointestinal cancers, Colorectal tumors)

  • COLORECTAL CANCER HIGH-RISK

    10

    Hereditary COLORECTAL CANCER HIGH-RISK PANEL

    Description

    The PreSENTIA hereditary colorectal cancer high-risk panel tests for numerous genetic mutations that could cause colorectal cancers in the future. Identifying mutations in these genes empowers healthcare providers and patients, as it allows them to take better and more informed decisions.

    Who is this test for?

    According to genetic testing guidelines, people who might benefit from genetic testing for hereditary colorectal cancers are those that have:

    • At least 1 first-degree family member with colorectal cancer
    • Personal or family history of colorectal polyps or colorectal cancer
    • Personal history of a confirmed or suspected hereditary colorectal cancer syndrome
    • Family members diagnosed with cancer at a young age
    • Family members diagnosed with rare forms of cancer
    • Multiple cancers in the same family member
    • At least one family member with genetic testing confirming genetic mutation
    • History of previous malignancies

    TAT:
    2-3 weeks
    Sample:
    Buccal Swab
    No of Genes Tested:
    10
    No of related hereditary cancer syndromes:
    6

    Genes Tested

    APC, MSH6, BMPR1A, MUTYH, EPCAM, PMS2, MLH1, SMAD4, MSH2, STK11

    Hereditary Cancer Syndromes associated with this panel:

    • Familial Adenomatous Polyposis / Attenuated Familial Adenomatous Polyposis (APC) (Associated cancers: Gastric, Pancreatic, Colorectal, Osteomas, Small Bowel)
    • Lynch syndrome (MLH1, MSH2, MSH6, PMS2, EPCAM) (Associated cancers: Colorectal, Endometrial, Stomach, Ovarian, Prostate, Pancreatic, Renal)
    • Peutz-Jeghers syndrome (STK11) (Associated cancers: Breast, Ovarian, Endometrial, Colorectal, Gastric, Pancreatic)
    • MUTYH-associated polyposis syndrome (MUTYH) (Associated cancer: Colorectal)
    • Juvenile Polyposis syndrome (SMAD4, BMPR1A) (Associated cancers: Colorectal, Gastric, Pancreatic)
    • Constitutional Mismatch Repair syndrome (MSH2, MSH6, MLH1, PMS2) (Associated cancers: Hematologic malignancies, Brain tumors, Gastrointestinal cancers, Colorectal)

  • COLORECTAL
    NON-POLYPOSIS

    5

    HEREDITARY NON-POLYPOSIS COLORECTAL CANCER PANEL

    Description

    The PreSENTIA hereditary colorectal non-polyposis cancer panel tests for numerous genetic mutations that could cause colorectal cancers in the future. Identifying mutations in these genes empowers healthcare providers and patients, as it allows them to take better and more informed decisions.

    Who is this test for?

    According to genetic testing guidelines, people who might benefit from genetic testing for hereditary colorectal cancers are those that have:

    • At least 1 first-degree family member with colorectal cancer
    • Personal or family history of colorectal polyps or colorectal cancer
    • Personal history of a confirmed or suspected hereditary colorectal cancer syndrome
    • Family members diagnosed with cancer at a young age
    • Family members diagnosed with rare forms of cancer
    • Multiple cancers in the same family member
    • At least one relative with genetic testing confirming genetic mutation
    • History of previous malignancies

    TAT:
    2-3 weeks
    Sample:
    Buccal Swab
    No of Genes Tested:
    5
    No of related hereditary cancer syndromes:
    2

    Genes Tested

    EPCAM, MSH6, MLH1, PMS2, MSH2

    Hereditary Cancer Syndromes associated with this panel:

    • Lynch syndrome (MLH1, MSH2, MSH6, PMS2, EPCAM) (Associated cancers: Colorectal, Endometrial, Stomach, Ovarian, Prostate, Pancreatic, Renal)
    • Constitutional Mismatch Repair syndrome (MSH2, MSH6, MLH1, PMS2) (Associated cancers: Hematologic malignancies, Brain tumors, Gastrointestinal cancers, Colorectal tumors)

  • COLORECTAL POLYPOSIS SYNDROME

    5

    HEREDITARY POLYPOSIS COLORECTAL CANCER PANEL

    Description

    The PreSENTIA hereditary polyposis colorectal cancer panel tests for numerous genetic mutations that could cause colorectal cancers in the future. Identifying mutations in these genes empowers healthcare providers and patients, as it allows them to take better and more informed decisions.

    Who is this test for?

    According to genetic testing guidelines, people who might benefit from genetic testing for hereditary polyposis colorectal cancers are those that have:

    • At least 1 first-degree family member with colorectal cancer
    • Personal or family history of colorectal polyps or colorectal cancer
    • Personal history of a confirmed or suspected hereditary colorectal cancer syndrome
    • Family members diagnosed with cancer at a young age
    • Family members diagnosed with rare forms of cancer
    • Multiple cancers in the same family member
    • At least one family member with genetic testing confirming genetic mutation
    • History of previous malignancies

    TAT:
    2-3 weeks
    Sample:
    Buccal Swab
    No of Genes Tested:
    5
    No of related hereditary cancer syndromes:
    4

    Genes Tested

    APC, SMAD4, BMPR1A, STK11, MUTYH

    Hereditary Cancer Syndromes associated with this panel:

    • Familial Adenomatous Polyposis / Attenuated Familial Adenomatous Polyposis (APC) (Associated cancers: Gastric, Pancreatic, Colorectal, Osteomas, Small Bowel)
    • Peutz-Jeghers syndrome (STK11) (Associated cancers: Breast, Ovarian, Endometrial, Colorectal, Gastric, Pancreatic)
    • MUTYH-associated polyposis syndrome (MUTYH) (Associated cancer: Colorectal)
    • Juvenile Polyposis syndrome (SMAD4, BMPR1A) (Associated cancers: Colorectal, Gastric, Pancreatic)

  • MYELODYSPLASTIC SYNDROME/LEUKEMIA

    24

    PreSENTIA HEREDITARY MYELODYSPLASTIC SYNDROME / LEUKEMIA CANCER PANEL

    Description

    The PreSENTIA hereditary myelodysplastic syndrome / leukemia cancer panel tests for numerous genetic mutations that could cause blood cancers in the future. Identifying mutations in these genes empowers healthcare providers and patients, as it allows them to take better and more informed decisions.

    Who is this test for?

    According to genetic testing guidelines, people who might benefit from genetic testing for hereditary myelodysplastic syndromes or leukemias are those that have:

    • Family history of a hereditary cancer syndrome associated with leukemia
    • Personal history of a hereditary cancer syndrome associated with leukemia
    • An identical twin who developed leukemia in the first year of life
    • A family member with a confirmed genetic mutation associated with hereditary leukemia

    TAT:
    2-3 weeks
    Sample:
    Buccal Swab
    No of Genes Tested:
    24
    No of related hereditary cancer syndromes:
    6

    Genes Tested

    ATM, FANCA, FANCG, MSH6, BRCA1, FANCB, FANCI, PALB2, BRCA2, FANCC, FANCL, PMS2, BRIP1, FANCD2, FANCM, RAD51C, EPCAM, FANCE, MLH1, SLX4, ERCC4, FANCF, MSH2, TP53

    Hereditary Cancer Syndromes associated with this panel:

    • Fanconi Anemia syndrome (FANCA, FANCB, FANCC, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCL, FANCM, SLX4, ERCC4, BRCA1, BRCA2, BRIP1, PALB2, RAD51C) (Associated cancers: Leukemia, Tumors of the head and neck, Gastrointestinal)
    • Constitutional Mismatch Repair Syndrome (MSH2, MSH6, MLH1, PMS2) (Associated cancers: Hematologic malignancies, Brain tumors, Gastrointestinal cancers, Colorectal Tumors)
    • Li-Fraumeni syndrome (TP53) (Associated cancers: Breast, Ovarian, Prostate, Pancreatic, Colorectal, Gastric, Renal, Sarcomas, Brain tumors, Lung, Leukemia)
    • Ataxia-telangiectasia syndrome (ATM) (Associated cancers: Leukemia, lymphoma)
    • Lynch Syndrome (MLH1, MSH2, MSH6, PMS2, EPCAM) (Associated cancers: Colorectal, Endometrial, Stomach, Ovarian, Prostate, Pancreatic, Renal)
    • Hereditary Breast & Ovarian syndrome (BRCA1 & BRCA2) (Associated cancers: Breast, Ovarian, Prostate, Pancreatic, Melanoma, Stomach, Esophagus)

  • GASTRIC

    14

    HEREDITARY GASTRIC CANCER PANEL

    Description

    The PreSENTIA hereditary Gastric cancer panel tests for numerous inherited genetic mutations that could cause gastric (stomach) cancers in the future. Identifying these mutations empowers healthcare providers and patients, as it allows them to take better and more informed decisions.

    Who is this test for?

    According to genetic testing guidelines, people who might benefit from genetic testing for gastric cancers are those that have:

    • Several family members in the same side of the family with gastric cancer
    • Personal or family history of a hereditary cancer syndrome linked to gastric cancer
    • A family member that has been diagnosed with a genetic mutation that has gastric cancer susceptibility

    TAT:
    2-3 weeks
    Sample:
    Buccal Swab
    No of Genes Tested:
    14
    No of related hereditary cancer syndromes:
    6

    Genes Tested

    APC, MSH2, SDHD, BMPR1A, MSH6, SMAD4, CDH1, PMS2, STK11, EPCAM, SDHB, TP53, MLH1, SDHC

    Hereditary Cancer Syndromes associated with this panel:

    • Hereditary diffuse gastric syndrome (CDH1) (Associated cancers: Gastric, Breast)
    • Li-Fraumeni syndrome (TP53) (Associated cancers: Breast, Ovarian, Prostate, Pancreatic, Colorectal, Gastric, Renal, Sarcomas, Brain tumors, Lung, Leukemia)
    • Lynch syndrome (MLH1, MSH2, MSH6, PMS2, EPCAM) (Associated cancers: Colorectal, Endometrial, Gastric, Ovarian, Prostate, Pancreatic, Renal)
    • Juvenile Polyposis syndrome (SMAD4, BMPR1A) (Associated cancers: Colorectal, Gastric, Pancreatic)
    • Familial Adenomatous Polyposis / Attenuated Familial Adenomatous Polyposis (APC) (Associated cancers: Gastric, Pancreatic, Colorectal, Osteomas, Small Bowel)
    • Peutz-Jeghers syndrome (STK11) (Associated cancers: Breast, Ovarian, Endometrial, Colorectal, Gastric, Pancreatic)

  • PROSTATE

    15

    PreSENTIA HEREDITARY PROSTATE CANCER PANEL

    Description

    The PreSENTIA hereditary prostate cancer panel tests for numerous genetic mutations that could cause prostate cancers in the future. Identifying mutations in these genes empowers healthcare providers and patients, as it allows them to take better and more informed decisions.

    Who is this test for?

    According to genetic testing guidelines, people who might benefit from genetic testing for hereditary colorectal cancers are those that have:

    • Several first-degree family members with prostate cancer
    • Family members diagnosed with prostate cancer at young age
    • Family members diagnosed with other cancer types, including breast, ovarian and pancreatic
    • Multiple cancers in the same family member
    • At least one family member with genetic testing confirming genetic mutation.
    • History of previous malignancies

    TAT:
    2-3 weeks
    Sample:
    Buccal Swab
    No of Genes Tested:
    15
    No of related hereditary cancer syndromes:
    5

    Genes Tested

    ATM, HOXB13, PALB2, BRCA1, MLH1, PMS2, BRCA2, MSH2, PTEN, CHEK2, MSH6, RAD51D, EPCAM, NBN, TP53

    Hereditary Cancer Syndromes associated with this panel:

    • Hereditary Breast & Ovarian cancer syndrome (BRCA1, BRCA2) (Associated cancers: Breast, Ovarian, Prostate, Pancreatic, Melanoma, Gastric, Esophagus)
    • Lynch syndrome (MLH1, MSH2, MSH6, PMS2, EPCAM) (Associated cancers: Colorectal, Endometrial, Gastric, Ovarian, Prostate, Pancreatic, Renal)
    • Li-Fraumeni syndrome (TP53) (Associated cancers: Breast, Ovarian, Prostate, Pancreatic, Colorectal, Gastric, Renal, Sarcomas, Brain tumors, Lung, Leukemia)
    • Li-Fraumeni syndrome 2 (CHEK2) (Associated cancers: Breast, Sarcomas, Brain tumors)
    • Ataxia-Telangiectasia syndrome (ATM) (Associated cancers: Leukemia Lymphoma)

  • PANCREATIC

    17

    HEREDITARY PANCREATIC CANCER PANEL

    Description

    The PreSENTIA hereditary Pancreatic cancer panel tests for numerous inherited genetic mutations that could cause pancreatic cancers in the future. Identifying these mutations empowers healthcare providers and patients, as it allows them to take better and more informed decisions.

    Who is this test for?

    According to genetic testing guidelines, people who might benefit from genetic testing for pancreatic cancers are those that have:

    • Several family members in the same side of the family with pancreatic cancer
    • Personal or family history of a hereditary cancer syndrome linked to pancreatic cancer
    • A family member that has been diagnosed with a genetic mutation that has pancreatic cancer susceptibility

    TAT:
    2-3 weeks
    Sample:
    Buccal Swab
    No of Genes Tested:
    17
    No of related hereditary cancer syndromes:
    9

    Genes Tested

    APC, CDK4, MLH1, SMAD4, ATM, CDKN2A, (CDKN2Ap16(INK4A), CDKN2Ap14(ARF)), MSH2, STK11, BMPR1A, EPCAM, MSH6, TP53, BRCA1, MEN1, PALB2, PMS2, BRCA2

    Hereditary Cancer Syndromes associated with this panel:

    • Hereditary Melanoma-Pancreatic cancer syndrome (CDKN2A, CDK4) (Associated cancers: Melanoma, pancreatic cancer, breast cancer)
    • Hereditary breast & ovarian cancer syndrome (BRCA1, BRCA2) (Associated cancers: Breast, Ovarian, Prostate, Pancreatic, Melanoma, Gastric, Esophagus)
    • Lynch syndrome (MLH1, MSH2, MSH6, PMS2, EPCAM) (Associated cancers: Colorectal, Endometrial, Gastric, Ovarian, Prostate, Pancreatic, Renal)
    • Familial Adenomatous Polyposis / Attenuated Familial Adenomatous Polyposis (APC) (Associated cancers: Gastric, Pancreatic, Colorectal, Osteomas, Small Bowel)
    • Li-Fraumeni syndrome (TP53) (Associated cancers: Breast, Ovarian, Prostate, Pancreatic, Colorectal, Gastric, Renal, Sarcomas, Brain tumors, Lung, Leukemia)
    • Peutz-Jeghers syndrome (STK11) (Associated cancers: Breast, Ovarian, Endometrial, Colorectal, Gastric, Pancreatic)
    • Juvenile Polyposis syndrome (SMAD4, BMPR1A) (Associated cancers: Colorectal, Gastric, Pancreatic)
    • Multiple endocrine neoplasia type 1 (MEN1) (Associated cancers: Thyroid, Parathyroid)
    • Ataxia-Telangiectasia syndrome (ATM) (Associated cancers: Leukemia, lymphoma)

  • RENAL

    13

    PreSENTIA HEREDITARY RENAL CANCER PANEL

    Description

    The PreSENTIA hereditary renal cancer panel tests for numerous genetic mutations that could cause renal (kidney) cancers in the future. Identifying mutations in these genes empowers healthcare providers and patients, as it allows them to take better and more informed decisions.

    Who is this test for?

    According to genetic testing guidelines, people who might benefit from genetic testing for hereditary renal cancers are those that have:

    • Family members that have had renal cancer, especially at a young age
    • Family members with renal cancer in both kidneys
    • Family members diagnosed with a hereditary cancer syndrome associated with renal cancer
    • Personal history of a hereditary cancer syndrome associated with renal cancer
    • Multiple cancers in the same family member
    • A family member with a confirmed genetic mutation associated with hereditary renal cancer.
    • History of previous malignancies

    TAT:
    2-3 weeks
    Sample:
    Buccal Swab
    No of Genes Tested:
    13
    No of related hereditary cancer syndromes:
    5

    Genes Tested

    BAP1, TP53, EPCAM, VHL, MLH1, SDHB, MSH2, SDHC, MSH6, SDHD, PMS2, SDHAF2, PTEN

    Hereditary Cancer Syndromes associated with this panel:

    • Von-Hippel Lindau syndrome (VHL) (Associated cancers: Renal, Paraganglioma/Pheochromocytoma)
    • Lynch syndrome (MLH1, MSH2, MSH6, PMS2, EPCAM) (Associated cancers: Colorectal, Endometrial, Gastric, Ovarian, Prostate, Pancreatic, Renal)
    • BAP1 Mutation Associated Disease (BAP1) (Associated cancers: Skin, Eye, Renal, Mesothelioma)
    • PTEN Hamartoma syndrome (PTEN) (Associated cancers: Breast, Endometrial, Colorectal, Melanoma, Renal)
    • Li-Fraumeni syndrome (TP53) (Associated cancers: Breast, Ovarian, Prostate, Pancreatic, Colorectal, Gastric, Renal, Sarcomas, Brain tumors, Lung, Leukemia)

  • SKIN (XP-ASSOCIATED)

    9

    PreSENTIA HEREDITARY SKIN (XP-ASSOCIATED) CANCER PANEL

    Description

    The PreSENTIA hereditary Xeroderma Pigmentosum-related cancer panel tests for genetic mutations in numerous genes that could cause skin cancers in the future. Identifying mutations in this gene empowers healthcare providers and patients, as it allows them to take better and more informed decisions.

    Who is this test for?

    According to genetic testing guidelines, people who might benefit from genetic testing for Xeroderma Pigmentosum-related skin cancers are those that have:

    • Family or personal history of a hereditary cancer syndrome associated with skin cancers
    • A family member with a confirmed genetic mutation associated with Xeroderma Pigmentosum

    TAT:
    2-3 weeks
    Sample:
    Buccal Swab
    No of Genes Tested:
    9
    No of related hereditary cancer syndromes:
    1

    Genes Tested

    DDB2, ERCC5, ERCC1, POLH, ERCC2, XPA, ERCC3, XPC, ERCC4

    Hereditary Cancer Syndromes associated with this panel:

    • Xeroderma Pigmentosum syndrome (DDB2, ERCC1, ERCC2, ERCC3, ERCC4, ERCC5, POLH, XPA, XP) (Associated cancers: Non-Melanoma and Melanoma)

  • FAMILIAL MELANOMA

    7

    PreSENTIA HEREDITARY FAMILIAL MELANOMA CANCER PANEL

    Description

    The PreSENTIA hereditary familial melanoma cancer panel tests for numerous genetic mutations that could cause familial melanoma skin cancers in the future. Identifying mutations in these genes empowers healthcare providers and patients, as it allows them to take better and more informed decisions.

    Who is this test for?

    According to genetic testing guidelines, people who might benefit from genetic testing for hereditary melanoma cancers are those that have:

    • At least two first-degree family member who have had metastatic melanoma
    • At least one family member has had multiple melanomas
    • Family or personal history of a hereditary cancer syndrome associated with melanoma
    • A family member with a confirmed genetic mutation associated with hereditary melanoma

    TAT:
    2-3 weeks
    Sample:
    Buccal Swab
    No of Genes Tested:
    7
    No of related hereditary cancer syndromes:
    5

    Genes Tested

    BAP1, PTEN, BRCA2, RB1, CDK4, TP53, CDKN2A (CDKN2Ap16(INK4A), CDKN2Ap14(ARF))

    Hereditary Cancer Syndromes associated with this panel:

    • Hereditary Melanoma-Pancreatic cancer syndrome (CDKN2A, CDK4) (Associated cancers: Melanoma, Pancreatic, Breast)
    • Retinoblastoma (RB1) (Associated cancers: Eye, Bone)
    • BAP1 Mutation Associated Disease (BAP1) (Associated cancers: Skin, Eye, Renal, Mesothelioma)
    • PTEN Hamartoma syndrome (PTEN) (Associated cancers: Breast, Endometrial, Colorectal, Melanoma, Renal)
    • Li-Fraumeni syndrome (TP53) (Associated cancers: Breast, Ovarian, Prostate, Pancreatic, Colorectal, Gastric, Renal, Sarcomas, Brain tumors, Lung, Leukemia)

  • PARAGANGLI­OMA / PHEOCHROMO­CYTOMA

    6

    PreSENTIA HEREDITARY PARAGANGLIOMA / PHEOCHROMOCYTOMA CANCER PANEL

    Description

    The PreSENTIA hereditary Paraganglioma / Pheochromocytoma cancer panel tests for genetic mutations in numerous genes that could cause Paraganglioma or Pheochromocytoma cancer in the future. Identifying mutations in these genes empowers healthcare providers and patients, as it allows them to take better and more informed decisions.

    Who is this test for?

    According to genetic testing guidelines, people who might benefit from genetic testing for Paraganglioma or Pheochromocytoma cancers are those that have:

    • Family or personal history of a hereditary cancer syndrome associated with paraganglioma / pheochromocytoma cancers
    • A family member with a confirmed genetic mutation associated with hereditary paraganglioma / pheochromatoma cancer

    TAT:
    2-3 weeks
    Sample:
    Buccal Swab
    No of Genes Tested:
    6
    No of related hereditary cancer syndromes:
    3

    Genes Tested

    RET, SDHC, SDHAF2, SDHD, SDHB, VHL

    Hereditary Cancer Syndromes associated with this panel:

    • Von-Hippel Lindau syndrome (VHL) (Associated cancers: Renal, Paragangliomas, Pheochromocytomas)
    • Hereditary Paraganglioma – Pheochromocytoma syndrome (SDHD, SDHAF2, SDHC, SDHB) (Associated cancers: Renal, Thyroid)
    • Multiple endocrine neoplasia type 2 (RET) (Associated cancers: Thyroid, Pheochromocytoma)

  • PARATHYROID

    1

    PreSENTIA HEREDITARY PARATHYROID CANCER PANEL

    Description

    The PreSENTIA hereditary parathyroid cancer panel tests for numerous genetic mutations that could cause parathyroid cancers in the future. Identifying mutations in these genes empowers healthcare providers and patients, as it allows them to take better and more informed decisions.

    Who is this test for?

    According to genetic testing guidelines, people who might benefit from genetic testing for parathyroid cancers are those that have:

    • At least two first-degree family member who have had parathyroid tumors
    • A personal or family history of a hereditary cancer syndrome associated with parathyroid cancer
    • A family member with a confirmed genetic mutation associated with hereditary parathyroid cancer

    TAT:
    2-3 weeks
    Sample:
    Buccal Swab
    No of Genes Tested:
    1
    No of related hereditary cancer syndromes:
    1

    Genes Tested

    MEN1

    Hereditary Cancer Syndromes associated with this panel:

    • Multiple endocrine neoplasia type 1 (MEN1) (Associated cancers: Thyroid, Parathyroid)

  • THYROID

    1

    PreSENTIA HEREDITARY THYROID CANCER PANEL

    Description

    The PreSENTIA hereditary thyroid cancer panel tests for genetic mutations in the RET gene that could cause thyroid cancer in the future. Identifying mutations in this gene empowers healthcare providers and patients, as it allows them to take better and more informed decisions.

    Who is this test for?

    According to genetic testing guidelines, people who might benefit from genetic testing for parathyroid cancers are those that have:

    • At least one first-degree family member who has had thyroid cancer
    • A personal or family history of a hereditary cancer syndrome associated with thyroid cancer
    • A family member with a confirmed genetic mutation associated with hereditary thyroid cancer

    TAT:
    2-3 weeks
    Sample:
    Buccal Swab
    No of Genes Tested:
    1
    No of related hereditary cancer syndromes:
    1

    Genes Tested

    RET

    Hereditary Cancer Syndromes associated with this panel:

    • Multiple endocrine neoplasia type 2 (RET) (Associated cancers: Thyroid, Pheochromocytoma)

  • PAN-CANCER

    62

    PreSENTIA HEREDITARY PAN-CANCER PANEL

    Description

    The PreSENTIA hereditary pan-cancer panel tests for 62 inherited genetic mutations that could cause several cancers in the future. Identifying these mutations empowers healthcare providers and patients, as it allows them to take better and more informed decisions.

    Who is this test for?

    According to genetic testing guidelines, people who might benefit from genetic testing for hereditary cancers are those that have:

    • Several family members in the same side of the family with cancer
    • Multiple cancers in the same family member
    • Family members with early cancer onset
    • Family members with rare cancer types
    • Family members with an unusual type of cancer (breast cancer in a male)
    • Personal or family history of a hereditary cancer syndrome
    • Personal or family history of a confirmed genetic mutation with known cancer susceptibility
    • History of previous malignancies

    TAT:
    2-3 weeks
    Sample:
    Buccal Swab
    No of Genes Tested:
    62
    No of related hereditary cancer syndromes:
    24

    Genes Tested

    APC, ERCC2, MEN1, RB1, ATM, ERCC3, MLH1, RET, BAP1, ERCC4, MRE11, SDHAF2, BARD1, ERCC5, MSH2, SDHB, BMPR1A, FANCA, MSH6, SDHC, BRCA1, FANCB, MUTYH, SDHD, BRCA2, FANCC, NBN, SLX4, BRIP1, FANCD2, PALB2, SMAD4, CDH1, FANCE, PMS2, SMARCA4, CDK4, FANCF, POLD1, STK11, CDKN2A, (CDKN2Ap16(INK4A), CDKN2Ap14(ARF)), FANCG, POLE, TP53, CHEK2, FANCI, POLH, VHL, DDB2, FANCL, PTEN, XPA, DICER1, FANCM, RAD50, XPC, EPCAM, GREM1, RAD51C, ERCC1, HOXB13, RAD51D,

    Hereditary Cancer Syndromes associated with this panel:

    • Li-Fraumeni syndrome (TP53) (Associated cancers: Breast, Ovarian, Prostate, Pancreatic, Colorectal, Gastric, Renal, Sarcomas, Brain tumors, Lung, Leukemia)
    • Li-Fraumeni syndrome 2 (CHEK 2) (Associated cancer: Breast, Sarcomas and Brain Tumors)
    • Hereditary Breast & Ovarian cancer syndrome (BRCA1, BRCA2) (Associated cancers: Breast, Ovarian, Prostate, Pancreatic, Melanoma, Gastric, Esophagus)
    • Familial Adenomatous Polyposis / Attenuated Familial Adenomatous Polyposis (APC) (Associated cancers: Gastric, Pancreatic, Colorectal, Osteomas, Small Bowel)
    • MUTYH-associated polyposis syndrome (MUTYH) (Associated cancer: Colorectal)
    • Lynch syndrome (MLH1, MSH2, MSH6, PMS2, EPCAM) (Associated cancers: Colorectal, Endometrial, Gastric, Ovarian, Prostate, Pancreatic, Renal)
    • PTEN Hamartoma syndrome (PTEN) (Associated cancers: Breast, Endometrial, Colorectal, Melanoma, Renal)
    • Peutz-Jeghers syndrome (STK11) (Associated cancers: Breast, Ovarian, Endometrial, Colorectal, Gastric, Pancreatic)
    • Juvenile Polyposis syndrome (SMAD4, BMPR1A) (Associated cancers: Colorectal, Gastric, Pancreatic)
    • Fanconi Anemia syndrome (FANCA, FANCB, FANCC, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCL, FANCM, SLX4, ERCC4, BRCA1, BRCA2, BRIP1, PALB2, RAD51C) (Associated cancers: Leukemia, Tumors of the head and neck, Gastrointestinal)
    • Von-Hippel Lindau syndrome (VHL) (Associated cancers: Renal, Paraganglioma/Pheochromocytoma)
    • Retinoblastoma (RB1) (Associated cancers: Eye, Bone)
    • Xeroderma Pigmentosum syndrome (DDB2, ERCC1, ERCC2, ERCC3, ERCC4, ERCC5, POLH, XPA, XP) (Associated cancers: Non-Melanoma and Melanoma)
    • Hereditary Melanoma-Pancreatic cancer syndrome (CDKN2A, CDK4) (Associated cancers: Melanoma, pancreatic cancer, breast cancer)
    • Hereditary diffuse gastric syndrome (CDH1) (Associated cancers: Gastric, Breast)
    • DICER 1 syndrome (DICER1) (Associated cancers: Lung, Renal, Ovarian, Thyroid cancer
    • Polymerase Proofreading Associated syndrome (POLD1, POLE) (Associated cancers: Colorectal, Endometrial)
    • Multiple endocrine neoplasia type 1 (MEN1) (Associated cancers: Thyroid, Parathyroid)
    • Multiple endocrine neoplasia type 2 (RET) (Associated cancers: Thyroid, Pheochromocytoma)
    • BAP1 Mutation Associated Disease (BAP1) (Associated cancers: Skin, Eye, Renal, Mesothelioma)
    • Ataxia-telangiectasia syndrome (ATM) (Associated cancers: Leukemia, Lymphoma)
    • Hereditary mixed polyposis syndrome (GREM1) (Associated cancer: Colorectal)
    • Constitutional mismatch repair syndrome (MSH2, MSH6, MLH1, PMS2) (Associated cancers: Hematologic malignancies, Brain tumors, Gastrointestinal cancers, Colorectal tumors)
    • Hereditary Paraganglioma – Pheochromocytoma syndrome (SDHD, SDHAF2, SDHC, SDHB) (Associated cancers: Renal, Thyroid, Paragangliomas, Pheochromocytomas)

  • HEREDITARY SYNDROMES

    Cancer Predisposing Syndromes & Associated Genes Associated Cancers PreSENTIA Hereditary Cancer Panel
    Li-Fraumeni syndrome
    TP53
    Breast, Ovarian, Prostate, Pancreatic, Colorectal, Gastric, Renal, Sarcomas, Brain, Lung, Leukemia
    • 3 Breast/Gynaecological Cancer Panels
    • Colorectal Cancer Panel
    • Gastric Cancer Panel
    • Familial Melanoma Cancer Panel
    • Myelodysplastic syndrome / Leukemia Cancer Panel
    • Pancreatic Cancer Panel
    • Prostate Cancer Panel
    • Renal Cancer Panel
    • Pan-Cancer Panel
    Li-Fraumeni syndrome 2
    CHEK2
    Breast, Sarcoma, Brain
    • 2 Breast/Gynaecological Cancer Panels
    • Colorectal Cancer Panel
    • Prostate Cancer Panel
    • Pan-Cancer Panel
    Hereditary breast and ovarian cancer syndrome
    BRCA1, BRCA2
    Breast, Ovarian, Prostate, Pancreatic, Melanoma, Gastric, Esophagus
    • 4 Breast/Gynaecological Cancer Panels
    • Myelodysplastic syndrome / Leukemia Cancer Panel
    • Pancreatic Cancer Panel
    • Prostate Cancer Panel
    • Pan-Cancer Panel
    Familial adenomatous polyposis/Attenuated familial adenomatous polyposis syndrome
    APC
    Gastric, Pancreatic, Colorectal, Osteomas, Small Bowel
    • 3 Colorectal Cancer Panels
    • Gastric Cancer Panel
    • Pancreatic Cancer Panel
    • Pan-Cancer Panel
    MUTYH-associated polyposis syndrome
    MUTYH
    Colorectal
    • Breast/Gynaecological Cancer Panel
    • 3 Colorectal Cancer Panels
    • Pan-Cancer Panel
    Lynch syndrome
    MLH1, MSH2, MSH6, PMS2, EPCAM
    Colorectal, Endometrial, Gastric, Ovarian, Prostate, Pancreatic, Renal
    • 2 Breast/Gynaecological Cancer Panels
    • 3 Colorectal Cancer Panels
    • Gastric Cancer Panel
    • Myelodysplastic syndrome / Leukemia Cancer Panel
    • Pancreatic Cancer Panel
    • Prostate Cancer Panel
    • Renal Cancer Panel
    • Pan-Cancer Panel
    PTEN hamartoma syndrome
    PTEN
    Breast, Endometrial, Colorectal, Melanoma, Renal
    • 3 Breast/Gynaecological Cancer Panels
    • Colorectal Cancer Panel
    • Familial Melanoma Cancer Panel
    • Renal Cancer Panel
    • Pan-Cancer Panel
    Peutz-Jeghers syndrome
    STK11
    Breast, Ovarian, Endometrial, Colorectal, Gastric, Pancreatic
    • 3 Breast/Gynaecological Cancer Panels
    • 3 Colorectal Cancer Panels
    • Gastric Cancer Panel
    • Pancreatic Cancer Panel
    • Pan-Cancer Panel
    Juvenile polyposis syndrome
    SMAD4, BMPR1A
    Colorectal, Gastric, Pancreatic
    • 3 Colorectal Cancer Panel
    • Gastric Cancer Panel
    • Pancreatic Cancer Panel
    • Pan-Cancer Panel
    Fanconi anemia syndrome
    FANCA, FANCB, FANCC, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCL, FANCM, SLX4, ERCC4, BRCA1, BRCA2, BRIP1, PALB2, RAD51C
    Leukemia, Tumors of the head & neck, Gastrointestinal
    • Myelodysplastic syndrome / Leukemia Cancer Panel
    • Pan-Cancer Panel
    Von-Hippel Lindau syndrome
    VHL
    Renal, Paragangliomas, Pheochromocytomas
    • Paraganglioma/Pheochromocytoma Cancer Panel
    • Renal Cancer Panel
    • Pan-Cancer Panel
    Retinoblastoma
    RB1
    Eye & bone
    • Familial Melanoma Cancer Panel
    • Pan-Cancer Panel
    Xeroderma pigmentosum syndrome
    DDB2, ERCC1, ERCC2, ERCC3, ERCC4, ERCC5, POLH, XPA,XPC
    Non-Melanoma & Melanoma
    • Skin (XP-associated) Cancer Panel
    • Pan-Cancer Panel
    Hereditary melanoma-pancreatic cancer syndrome
    CDKN2A, CDK4
    Melanoma, Pancreatic & Breast
    • Familial Melanoma Cancer Panel
    • Pancreatic Cancer Panel
    • Pan-Cancer Panel
    Hereditary diffuse gastric syndrome
    CDH1
    Gastric & Breast
    • 3 Breast/Gynecological Cancer Panels
    • Colorectal Cancer Panel
    • Gastric Cancer Panel
    • Pan-Cancer Panel
    DICER 1 syndrome
    DICER1
    Lung, Renal, Ovarian, Thyroid
    • Breast/Gynecological Cancer Panel
    • Pan-Cancer Panel
    Polymerase Proofreading Associated syndrome
    POLD1, POLE
    Colorectal & Endometrial
    • Breast/Gynecological Cancer Panel
    • Colorectal Cancer Panel
    • Pan-Cancer Panel
    Multiple Endocrine Neoplasia (MEN) syndrome type 1
    MEN1
    Parathyroid & Pancreatic
    • Pancreatic Cancer Panel
    • Parathyroid Cancer Panel
    • Pan-Cancer Panel
    Multiple Endocrine Neoplasia (MEN) syndrome type 2
    RET
    Thyroid & Pheochromocytoma
    • Paraganglioma / Pheochromocytoma Cancer Panel
    • Thyroid Cancer Panel
    • Pan-Cancer Panel
    BAP1 mutation associated disease
    BAP1
    Skin, Eye, Kidney, Mesothelioma
    • Familial Melanoma Cancer Panel
    • Renal Cancer Panel
    • Pan-Cancer Panel
    Ataxia-telangiectasia syndrome
    ATM
    Leukemia & Lymphoma
    • 2 Breast/Gynaecological Cancer Panels
    • Pancreatic Cancer Panel
    • Prostate Cancer Panel
    • Myelodysplastic syndrome / Leukemia Cancer Panel
    • Pan-Cancer Panel
    Hereditary-mixed polyposis syndrome
    GREM1
    Colorectal
    • Colorectal Cancer Panel
    • Pan-Cancer Panel
    Constitutional mismatch repair syndrome
    MSH2, MSH6, MLH1, PMS2
    Hematologic malignancies, Brain, Gastrointestinal, Colorectal
    • 2 Breast/Gynecological Cancer Panels
    • 3 Colorectal Cancer Panels
    • Myelodysplastic syndrome / Leukemia Cancer Panel
    • Pan-Cancer Panel
    Hereditary Paraganglioma – Pheochromocytoma syndrome
    SDHAF2, SDHB, SDHC, SDHD
    Renal, Thyroid, Paragangliomas, Pheochromocytomas
    • Paraganglioma / Pheochromocytoma Cancer Panel
    • Renal Cancer Panel
    • Pan-Cancer Panel

HOW TO ADMINISTER PreSENTIA?

  • RECOMMEND THE IDEAL PANEL TO YOUR PATIENT
  • COLLECT A BUCCAL SWAB FROM YOUR PATIENT
  • SEND THE SAMPLE TO OUR LABORATORY
  • THE SAMPLE WILL BE ANALYZED IN OUR LABORATORY
  • RESULTS WILL BE SENT TO YOU WITHIN 2-3 WEEKS

NIPD Genetics - Privacy Policy

General Statement

This Privacy Policy applies only to www.nipd.com and its subdomains (hereafter collectively referred to as “Sites") that link to this policy. NIPD Genetics Sites are owned by NIPD Genetics Public Company Ltd and are operated by NIPD Genetics Public Company Ltd and on occasion by a third-party that is responsible for the technical maintenance of the Sites.

If, you do not agree with this Privacy Policy, please do not access or use any of NIPD Genetics Sites.

NIPD Genetics values your interest in NIPD Genetics, its products and its services. NIPD Genetics takes the protection of your data seriously.

Personal data for purposes of this Privacy Policy, is any information by which you can be individually identified, including, but not limited to, your name, profession, address, e-mail address, and telephone number.

You may contact NIPD Genetics Public Company Ltd at
NIPD Genetics Public Company Ltd
Neas Engomis 31
Engomi, Nicosia
2409, Cyprus

NIPD Genetics Data Protection Officer can be reached at dpo@nipd.com

This Privacy Policy applies only to the Sites as defined above and which are operated by NIPD Genetics. The NIPD Genetics Privacy Policy seeks to inform the users of its Sites of the following:

NIPD Genetics will not use or share your information with anyone, except as described in this Privacy Policy. This Privacy Policy does not apply to any information we might collect by other digital and offline means and or from other digital and offline sources. The use of information collected through our Sites shall be limited to the purposes under this Privacy Policy and our Terms of Use to customers.

This page informs you of our policies regarding the collection, use, and disclosure of personal data when you use our Sites and the choices you have associated with that data.

We use your data to provide and improve the Sites. By using the Sites, you agree to the collection and use of information in accordance with this policy. Unless otherwise defined in this Privacy Policy, terms used in this Privacy Policy have the same meanings as in our Terms and Conditions, accessible from www.nipd.com

Type of personal information NIPD Genetics may collect through its Sites

Information Collection And Use

We collect several different types of information for various purposes to provide and improve our Sites and services to you.

Personal Data

While using NIPD Genetics Sites, you may be asked to provide NIPD Genetics certain personally identifiable information that can be used to contact or identify you ("Personal Information"). Personal Information that might be used to identify you includes, but is not limited to:

If you send us a query via our Contact us form, your email address, the content and any follow up emails are retained indefinitely.

Cookies and Usage Data

Usage Data

We may also collect information how the Sites are accessed and used ("Usage Data"). This Usage Data may include information such as your computer's Internet Protocol address (e.g. IP address), browser type, browser version, the pages of our Sites that you visit, the time and date of your visit, the time spent on those pages, unique device identifiers and other diagnostic data.

Tracking & Cookies Data

We use cookies and similar tracking technologies to track the activity on our Sites and hold certain information.

Cookies are files with small amount of data which may include an anonymous unique identifier. Cookies are sent to your browser from a website and stored on your device. Tracking technologies also used are beacons, tags, and scripts to collect and track information and to improve and analyze our Sites.

You can instruct your browser to refuse all cookies or to indicate when a cookie is being sent. However, if you do not accept cookies, you may not be able to use some portions of our Sites.

Examples of Cookies we use:

Session Cookies. We use Session Cookies to operate our Sites.

Preference Cookies. We use Preference Cookies to remember your preferences and various settings.

Security Cookies. We use Security Cookies for security purposes.

Visitor behavior cookies. To understand how visitors use and navigate the Sites

Keyword cookies. To understand how visitors discover the Sites.

Use of Data

www.nipd.com uses the collected data for various purposes:

Transfer of Data

Your information, including personal data, may be transferred to — and maintained on — computers located outside of your province, country or other governmental jurisdiction where the data protection laws may differ than those from your jurisdiction.

If you are located outside Cyprus and choose to provide information to us, please note that we transfer the data, including personal data, to Cyprus and process it there.

Your consent to this Privacy Policy followed by your submission of such information represents your agreement to that transfer.

www.nipd.com will take all reasonable steps necessary to ensure that your data is treated securely and in accordance with this Privacy Policy and no transfer of your personal data will take place to an organization or a country unless there are adequate controls in place including the security of your data and other personal information.

Disclosure of Data

NIPD Genetics complies with the protection of personal data regulation and will not sale or trade your personal data.

NIPD Genetics may disclose your personal data in the good faith belief that such action is necessary to:

Security of Data

The security of your data is important to us, but remember that no method of transmission over the Internet, or method of electronic storage is 100% secure. While we strive to use commercially acceptable means to protect your Personal Data, we cannot guarantee its absolute security.

Service Providers

We may employ third party companies and individuals to facilitate, maintain or operate our Sites ("Service Providers"), to provide the SItes on our behalf, to perform service-related services or to assist us in analyzing how our Sites is used.

These third parties have access to your Personal Data only to perform these tasks on our behalf and are obligated not to disclose or use it for any other purpose.

Analytics

We may use third-party Service Providers to monitor and analyze the use of our Sites.

Google Analytics

Google Analytics is a web analytics service offered by Google that tracks and reports website traffic. Google uses the data collected to track and monitor the use of our Service. This data is shared with other Google services. Google may use the collected data to contextualize and personalize the ads of its own advertising network.

You can opt-out of having made your activity on the Service available to Google Analytics by installing the Google Analytics opt-out browser add-on. The add-on prevents the Google Analytics JavaScript (ga.js, analytics.js, and dc.js) from sharing information with Google Analytics about visits activity.

For more information on the privacy practices of Google, please visit the Google Privacy & Terms web page

Access to your personal data, correction, deletion, and Opting Out

You have the right to review, update or delete any of your personal data by sending a request at NIPD Genetics Personal Data Officer pdo@nipd.com

Links to Other Sites

Our Sites may contain links to other sites that are not operated by us. If you click on a third-party link, you will be directed to that third party's site. We strongly advise you to review the Privacy Policy of every site you visit.

We have no control over and assume no responsibility for the content, privacy policies or practices of any third-party sites or services.

Children's Privacy

Our Service does not address anyone under the age of 18 ("Children").

We do not knowingly collect personally identifiable information from anyone under the age of 18. If you are a parent or guardian and you are aware that your Children has provided us with Personal Data, please contact us. If we become aware that we have collected Personal Data from children without verification of parental consent, we take steps to remove that information from our servers.

Changes to This Privacy Policy

We may update our Privacy Policy from time to time. We will notify you of any changes by posting the new Privacy Policy on this page.

We will let you know via email and/or a prominent notice on our Service, prior to the change becoming effective and update the "effective date" at the top of this Privacy Policy.

You are advised to review this Privacy Policy periodically for any changes. Changes to this Privacy Policy are effective when they are posted on this page.

Contact Us

If you have any questions about this Privacy Policy, please contact pdo@nipd.com

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